Compliance Manager – Pharmaceuticals

We are seeking an experienced Senior Compliance Manager to support GMP compliance and inspection readiness within a regulated pharmaceutical environment. This is an exciting opportunity to play a key role in ensuring regulatory excellence and maintaining high standards of quality across the organisation.
In this role, you will be responsible for ensuring ongoing compliance with EU/UK GMP and Isle of Man regulatory requirements, while maintaining and continuously improving the Pharmaceutical Quality System (PQS). You will provide oversight of deviations, CAPAs, change control, audits, and inspections, acting as a key contact during MHRA and Isle of Man regulatory inspections. You will also ensure data integrity in line with ALCOA++ principles and promote a strong culture of quality and compliance across the business.
You will work closely with cross-functional teams including Manufacturing, Quality Control, Quality Assurance, Engineering, and Supply Chain to embed compliance into daily operations. The role also involves providing compliance guidance during investigations, deviations, validation activities, and change initiatives, as well as supporting training programmes to ensure personnel remain inspection-ready.
A key part of the position will be driving continuous improvement and inspection readiness. You will monitor regulatory updates and emerging compliance expectations, identify risks, and implement proactive mitigation strategies. You will also support initiatives that enhance compliance maturity and improve inspection outcomes.
The successful candidate will have a minimum of five years’ experience in the pharmaceutical industry within a GMP-regulated environment, along with strong knowledge of EU/UK GMP, data integrity requirements, and regulatory inspection processes. You should have hands-on experience managing deviations, CAPAs, change control, audits, and inspections, as well as experience in GMP compliance, quality assurance, or quality systems management. The applicant will be subject to a satisfactory Enhanced DBS check.
Additional desirable experience includes supporting or hosting MHRA or Isle of Man inspections, knowledge of GDP and Responsible Person (RP) functions, and experience with electronic quality systems and computerised system compliance. A degree in Pharmaceutical Science, Chemistry, Biology, or a related discipline is also preferred.
You will bring a strong regulatory mindset, excellent attention to detail, and the ability to interpret and apply GMP requirements in a practical way. Strong communication and stakeholder management skills are essential, along with the ability to work independently and influence cross-functional teams. A high level of integrity and a focus on patient safety and product quality are critical for success in this role. To apply, please submit your CV along with a supporting statement or email for further details. All applications will be treated in the strictest confidence.
For more details and to apply contact info@manncann.com